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Home > Grand Challenge Seed Program > On-going Programs　　（Past Programs）
 
Division of Mathematics and Physical Sciences
Project No. Project Title Project Principal Investigator Affiliation Execution Period
AS-GCS-114-M01 Decipher how three-dimensional microenvironments mechanically control stem cell fateKeng-Hui LinInstitute of Physics, Academia Sinica2025/1/1 ~ 2028/12/31
AS-GCS-114-M02 BURSTT-2048: Solving the Mystery of Fast Radio BurstsUe-Li PenInstitute of Physics, Academia Sinica / Institute of Astronomy and Astrophysics, Academia Sinica / National Chung Hsing University / National Sun Yat-sen University / Carnegie Mellon University / National Tsing Hua University / Institute of Astronomy and Astrophysics Academia Sinica / National Taiwan University / Institute of Physics, Academia Sinica2025/1/1 ~ 2028/12/31
AS-GCS-114-M03 Spin-Orbit torque induced nearly lossless magnetic resonance Lee, Shang-Fan Institute of Physics, Academia Sinica 2025-01-01 ~ 2026-12-31
AS-GCS-114-M04 Developing a flexible connection scheme for superconducting qubit by flip-chip process Ke, Chung-Ting Institute of Physics, Academia Sinica / Research Center for Critical Issues, Academia Sinica / National Changhua University of Education / Research Center for Critical Issues, Academia Sinic 2025-01-01 ~ 2026-12-31
AS-GCS-114-M05 Design and fabricate miniature protein magnetic particles with ultra-efficient capture capability purposed for accelerating structural proteomics of rare or de novo RNA processing complexes Chang, Wei-Hau Institute of Chemistry, Academia Sinica / Institute of Statistical Science, Academia Sinica 2025-01-01 ~ 2025-12-31
AS-GCS-114-M06 Development of Broadband Polarization-Sensitive Superconducting Single-Photon Detectors for Quantum Key Distribution Lu, Yu-Jung The Research Center of Applied Sciences, Academia Sinica 2025-01-01 ~ 2026-12-31
AS-GCS-114-M07 One-stack Automated Single-cell Intelligence-empowered Analysis System (OASIS) Tung, Yi-Chung The Research Center of Applied Sciences, Academia Sinica 2025-01-01 ~ 2026-12-31
AS-GCS-113-M01 Unraveling the Complexity of Three-Dimensional Spatial Biology Through the Integration of Advanced Technologies Peilin Chen Research Center for Applied Sciences, Academia Sinica 2024-01-01 ~ 2025-12-31
AS-GCS-113-M02 Modulating macrophage polarization with H2-evolving systems for treating inflammatory diseases Yu-Jung Lin Research Center for Applied Sciences, Academia Sinica 2024-01-01 ~ 2025-12-31
AS-GCS-113-M03 Dynamic Chromatin Structures in Gene Expression Resolved by Advanced Microscopy Chia-Lung Hsieh Institute of Atomic and Molecular Sciences, Academia Sinica 2024-01-01 ~ 2025-12-31
AS-GCS-113-M04 Deciphering the Origins of Ultra-High Energy Cosmic Rays: Mitigating Magnetic Field Effects with Deep Learning Anatoli Fedynitch Institute of Physics, Academia Sinica 2024-01-01 ~ 2025-12-31
AS-GCS-113-M05 Identifying Holes of Arbitrary Dimensions and Quantifying their Distributions in Large-Scale Networks Chen-Hsiang Yeang Institute of Statistical Science 2024-01-01 ~ 2025-12-31
AS-GCS-113-M06 New Perspectives in Quantum Complexity and Automata Theory Kai-Min Chung Institute of Information Science 2024-01-01 ~ 2025-12-31
AS-GCS-113-M07 Efficient, Secure, Formally Verified Correct Postquantum Crypto Libraries Bo-Yin Yang Institute of Information Science 2024-01-01 ~ 2025-12-31
AS-GCS-112-M05 ncluding non equilibrium kinetics in pMHC-TCR interactions to improve in silico screening power and Spectrum for vaccine design and development Chin-Lin Guo Institute of Physics 2023-07-01 ~ 2025-06-30
AS-GCS-112-M06 Intelligent Q&A Agent Based on Large Language Models Lun-Wei Ku Institute of Information Science 2023-07-01 ~ 2025-06-30
Division of Life Sciences
Project No. Project Title Project Principal Investigator Affiliation Execution Period
AS-GCS-114-L01 Systemic identification of interaction network of plasma cellsKuo-I LinGenomics Research Center, Academia Sinica2025/1/1 ~ 2026/12/31
AS-GCS-114-L02 Investigating the Molecular Mechanisms of Reproductive Barriers in Plants with Wet Stigmas Jauh, Guang-Yuh Institute of Plant and Microbial Biology, Academia Sinica 2025-01-01 ~ 2026-12-31
AS-GCS-114-L03 Challenge to select a proper partner: mechanisms of sea anemone and clown fish symbiosis establishment. Khalturin, Konstantin Institute of Cellular and Organismic Biology, Academia Sinica 2025-01-01 ~ 2026-12-31
AS-GCS-114-L04 Systematic identification of genes and pathways regulating Siglec-15 expression Angata, Takashi Institute of Biological Chemistry, Academia Sinica 2025-01-01 ~ 2026-12-31
AS-GCS-114-L05 Revisiting the correlation between meiosis and hybrid sterility Wang, Ting-Fang Institute of Molecular Biology, Academia Sinica 2025-01-01 ~ 2026-12-31
AS-GCS-114-L06 Integrating Immunopeptidomics and Machine Learning for Identification of Key T Cell Epitopes and their corresponding TCR clones in CNS Immunity Cheng, Pei-Lin Institute of Molecular Biology, Academia Sinica 2025-01-01 ~ 2026-12-31
AS-GCS-114-L07 Developing Novel Parahydrogen-Hyperpolarized 19F-Pyruvate for Metabolic MRI. Hwang, Dennis Wen-Han Institute of Biomedical Sciences, Academia Sinica 2025-01-01 ~ 2026-12-31
AS-GCS-113-L01 Unraveling the Mystery of TRAX: A Novel Mechanism for Sorting miRNAs into Extracellular Vesicles in Huntington's Disease Yijuang Chern Institute of Biomedical Sciences, Academia Sinica 2024-01-01 ~ 2025-12-31
AS-GCS-113-L02 To study how microbial glycoconjugates are dynamically modified to orchestrate the host immune response Chun-Hung Lin Institute of Biological Chemistry, Academia Sinica 2024-01-01 ~ 2025-12-31
AS-GCS-113-L03 Mechanism of Ultrashort Intron Splicing with Reduced Spliceosomes Chien-Ling Lin Institute of Molecular Biology 2024-01-01 ~ 2025-12-31
AS-GCS-113-L04 Establish a high-throughput platform to generate, customize and validate CAR-NK cells Kuen-Phon Wu Institute of Biological Chemistry 2024-01-01 ~ 2025-12-31
AS-GCS-113-L05 Advancing Ubiquitin Biological Pathways through Deep Learning-Guided Protein Design Kuen-Phon Wu Institute of Biological Chemistry 2024-01-01 ~ 2025-12-31
AS-GCS-113-L06 Deciphering partial altitudinal migration in the Asian House Martin (Delichon dasypus): from genomics to physiology Chih-Ming Hung Biodiversity Research Center 2024-01-01 ~ 2025-12-31
AS-GCS-113-L07 Unveiling Root Nitrate Dynamics: Pioneering Precision for Sustainable Crop Enhancement Cheng-Hsun Ho Agricultural Biotechnology Research Center 2024-01-01 ~ 2025-12-31
AS-GCS-112-L02 Precise control of neuronal RNA splicing in the critical developmental window to counteract stress sensitization Pei-Lin Cheng Institute of Molecular Biologyy 2023-01-01 ~ 2025-12-31
Division of Humanities and Social Sciences
Project No. Project Title Project Principal Investigator Affiliation Execution Period
AS-GCS-114-H01 The Politics of Elemental and Volume: An Exploration of Geothermal Development in Taitung Wu, Ming-Jen Institute of Ethnology, Academia Sinica 2025-01-01 ~ 2026-12-31
AS-GCS-114-H02 Threat Perception towards China in the Eyes of the Public: A Cross-National Analysis of Six East Asian Countries Yeh, Kuang-Hui Institute of Ethnology, Academia Sinica / Institute of Political Science, Academia Sinica / Harvard University / National Taiwan University 2025-01-01 ~ 2025-12-31
AS-GCS-114-H03 Experimental Evidence on the Habit-Forming Effects of Electoral Systems Muraoka,Taishi Institute of Political Science, Academia Sinica / National Chengchi University / National Chengchi University 2025-01-01 ~ 2025-12-31
AS-GCS-113-H01 The Great Social Transformation in Southern Taiwan: Community-based Social, Economic, Cultural and Medical Care Integrated Research CHYI-IN WU, Zong-Rong Lee, Wei-Hsian Chi, Yi-Ting Chung, Hui-Ju Kuo, Chung-Ying Lin, Yun-Hsuan Chang Research Fellow, Associate Research Fellow, Assistant Professor 2024-01-01 ~ 2025-12-31
AS-GCS-113-H03 Media coverage of elite cues in policy persuasion Greg Chih-Hsin Sheen Institute of Political Science 2024-01-01 ~ 2025-12-31
AS-GCS-113-H04 Governing Generative AI for a Future Society Chih-hsing Ho Institute of European and American Studies 2024-01-01 ~ 2025-12-31
AS-GCS-113-H05 Reading and Scholarly Writing: Transformations in the Age of Developing Digital Technologies Ku-ming (Kevin) Chang Institute of History and Philology 2024-01-01 ~ 2025-12-31